CORRELATION BETWEEN MEAN SERUM C-REACTIVE PROTEIN (CRP) LEVEL AND MEAN LESION VOLUME IN ACUTE ISCHEMIC STROKE

Authors

  • Muhammad Zahid Younis Combined Military Hospital, Dera Ismail Khan, Pakistan
  • Ejaz Ahmed Mian Combined Military Hospital, Dera Ismail Khan, Pakistan
  • Syed Onaiz Zulfiqar Anwar Combined Military Hospital, Dera Ismail Khan, Pakistan
  • Fatima Naseem Combined Military Hospital, Dera Ismail Khan, Pakistan

Keywords:

Acute ischemic stroke, Correlation, Serum C-reactive protein (CRP), Mean lesion volume

Abstract

Objective: To determine the correlation between mean serum C-reactive protein (CRP) level and mean lesion volume in acute ischemic stroke.

Study Design: Cross sectional study.

Place and Duration of Study: This study was conducted at Department of Neurology and General Medicine Combined Military Hospital, Quetta, Pakistan, from Jan 2016 to Jul 2016.

Methodology: A total of 50 patients of both genders fulfilling the inclusion criteria were included in the study using non-probability consecutive sampling technique after taking informed consent. All patients were subjected to CT scan and infarct volume was calculated. Meanwhile blood samples were collected for CRP levels.

Results: 21 (42%) were between 18-50 years of age while 29 (58%) were between 51-80 years of age. Mean age was 52.46 ± 13.33 years, 31 (62%) were male and 19 (38%) were females, mean serum CRP level of the patients was 37.56 ± 30.78 mg/L, mean lesion volume in acute ischemic stroke cases as 7.5 ± 3.59, Pearson correlation coefficient of mean lesion volume and serum CRP in acute ischemic stroke was calculated r=0.9162 (p-value 0.01).

Conclusion: Correlation between CRP levels and infarction volume on CT scan in Acute Ischemic Stroke was found to be positive, therefore it may be used as a routine screening tool for estimation of infarct volume.

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Published

23-10-2019

Issue

Section

Original Articles

How to Cite

1.
Younis MZ, Mian EA, Anwar SOZ, Naseem F. CORRELATION BETWEEN MEAN SERUM C-REACTIVE PROTEIN (CRP) LEVEL AND MEAN LESION VOLUME IN ACUTE ISCHEMIC STROKE. Pak Armed Forces Med J [Internet]. 2019 Oct. 23 [cited 2024 Sep. 19];69(5):939-42. Available from: https://pafmj.org/PAFMJ/article/view/3390