CORRELATION BETWEEN MEAN SERUM C-REACTIVE PROTEIN (CRP) LEVEL AND MEAN LESION VOLUME IN ACUTE ISCHEMIC STROKE

  • Muhammad Zahid Younis Combined Military Hospital, Dera Ismail Khan, Pakistan
  • Ejaz Ahmed Mian Combined Military Hospital, Dera Ismail Khan, Pakistan
  • Syed Onaiz Zulfiqar Anwar Combined Military Hospital, Dera Ismail Khan, Pakistan
  • Fatima Naseem Combined Military Hospital, Dera Ismail Khan, Pakistan
Keywords: Acute ischemic stroke, Correlation, Serum C-reactive protein (CRP), Mean lesion volume

Abstract

Objective: To determine the correlation between mean serum C-reactive protein (CRP) level and mean lesion volume in acute ischemic stroke.

Study Design: Cross sectional study.

Place and Duration of Study: This study was conducted at Department of Neurology and General Medicine Combined Military Hospital, Quetta, Pakistan, from Jan 2016 to Jul 2016.

Methodology: A total of 50 patients of both genders fulfilling the inclusion criteria were included in the study using non-probability consecutive sampling technique after taking informed consent. All patients were subjected to CT scan and infarct volume was calculated. Meanwhile blood samples were collected for CRP levels.

Results: 21 (42%) were between 18-50 years of age while 29 (58%) were between 51-80 years of age. Mean age was 52.46 ± 13.33 years, 31 (62%) were male and 19 (38%) were females, mean serum CRP level of the patients was 37.56 ± 30.78 mg/L, mean lesion volume in acute ischemic stroke cases as 7.5 ± 3.59, Pearson correlation coefficient of mean lesion volume and serum CRP in acute ischemic stroke was calculated r=0.9162 (p-value 0.01).

Conclusion: Correlation between CRP levels and infarction volume on CT scan in Acute Ischemic Stroke was found to be positive, therefore it may be used as a routine screening tool for estimation of infarct volume.

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Published
2019-10-23
How to Cite
Younis, M., Mian, E., Anwar, S. O., & Naseem, F. (2019). CORRELATION BETWEEN MEAN SERUM C-REACTIVE PROTEIN (CRP) LEVEL AND MEAN LESION VOLUME IN ACUTE ISCHEMIC STROKE. PAFMJ, 69(5), 939-42. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/3390
Section
Original Articles