Frequency and Pattern of Thyroid Dysfunction in Patients with Polycystic Ovary Syndrome

  • Sadaf Naz Allama Iqbal Medical College, Lahore, Jinnah Hospital, Lahore, Pakistan
  • khurshid Ahmad khan Allama Iqbal Medical College, Lahore, Jinnah Hospital, Lahore, Pakistan
  • Amina Umer Allama Iqbal Medical College, Lahore, Jinnah Hospital, Lahore, Pakistan
  • Muhammad Tabish Raza Allama Iqbal Medical College, Lahore, Jinnah Hospital, Lahore, Pakistan
  • Khalid Mehmood Nasir Allama Iqbal Medical College, Lahore, Jinnah Hospital, Lahore, Pakistan
  • Imtiaz Hussain Allama Iqbal Medical College, Lahore, Jinnah Hospital, Lahore, Pakistan
Keywords: Anti-TPO, Polycystic ovarian syndrome, Thyroid autoimmunity, Thyroid dysfunction

Abstract

Objective: To determine the frequency and pattern of thyroid dysfunction in patients with polycystic ovary syndrome.

Study Design: Cross-sectional study.

Place and Duration of Study: Department of Endocrinology, Jinnah Hospital, Lahore Pakistan, from Jan from Jun 2017.

Methodology: Seventy-seven patients diagnosed with PCOS, based on Rotterdam criteria, were enrolled in the study. Thyroid function status was evaluated using measurement of serum thyroid-stimulating hormone (TSH), free T3, T4 and anti-thyroperoxidase (anti-TPO) antibodies.

Results: The mean age of the study population was 29.0±9.2 years. Out of 77 females with PCOS, 63(81.8%) were euthyroid, five (6.5%) patients were diagnosed with primary hypothyroidism, and nine (11.7%) were found to have subclinical hypothyroidism. Anti-TPO antibodies were detected in 18 patients (23.4%), including 12(19.0%) euthyroid females.

Conclusion: Thyroid dysfunction was found among patients with PCOS. Evidence of autoimmunity was seen even in euthyroid patients.

Downloads

Download data is not yet available.
Published
2022-11-04
How to Cite
Naz, S., khan, khurshid, Umer, A., Raza, M., Nasir, K., & Hussain, I. (2022). Frequency and Pattern of Thyroid Dysfunction in Patients with Polycystic Ovary Syndrome. Pakistan Armed Forces Medical Journal, 72(5), 1730-33. https://doi.org/10.51253/pafmj.v72i5.3288
Section
Original Articles