FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES

  • Hafiz Abdul Manaan Punjab Institute of Cardiology, Lahore Pakistan
  • Abdul Sattar Gujranwala Medical College, Gujranwala Pakistan
  • Imran Saleem Punjab Institute of Cardiology, Lahore Pakistan
  • Shamila Afshan Punjab Institute of Cardiology, Lahore Pakistan
Keywords: Atrioventricular block, High-grade heart block, Elevated troponin T, Non-ischemic heart block

Abstract

Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients.

Study Design: Prospective, cross-sectional analytical study.

Place and Duration of Study: This study conducted in the emergency department of Punjab Institute of cardiology, Lahore Pakistan, from Mar 2017 to Jun 2018.

Patients and Methods: Patients with advanced 2nd degree and 3rd degree AV blocks, diagnosed on a 12-lead electrocardiogram (ECG), and no ischemic changes on the ECG were included. hs-TnT levels were done for all patients. All patients filled a preformed questionnaire. Data were entered and analyzed using IBM-SPSS-23.

Results: Of the 138 patients recruited, 60.9% were male patients. The mean age of the study participants was 63.13 ± 14.73 years. Syncope was the most common presentation (78.3%). hs-TnT levels were elevated in 55.8% participants. Elevated Trop T levels were more common in male patients (63.6%). Elevated Trop T levels were significantly associated with co-morbidities including diabetes, hypertension, and smoking, and clinical presence of chest pain and syncope (p>0.05).

Conclusion: Patients with non-ischemic high-grade AV blocks present with syncope. Even in absence of ischemia, troponin levels were seen in many participants. Elevated Trop T levels cannot be considered pathognomonic for myocardial ischemia.

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Published
2019-08-27
How to Cite
Manaan, H., Sattar, A., Saleem, I., & Afshan, S. (2019). FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES. Pakistan Armed Forces Medical Journal, 69(4), 901-04. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/3222
Section
Original Articles