Frequency and Risk Factors of Meconium Aspiration Syndrome in Babies Delivered to Mothers with Meconium Stained Amniotic Fluid

Sidra Tanveer; Faisal Basheer; Arshad Khushdil; Fady MA Motlaq; Raazia Nawaz; Maria Javed

doi:10.51253/pafmj.v72iSUPPL-2.3184

Authors

Sidra Tanveer Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Faisal Basheer Combined Military Hospital Bahawalpur/National University of Medical Sciences (NUMS) Pakistan
Arshad Khushdil Combined Military Hospital Quetta/National University of Medical Sciences (NUMS) Pakistan
Fady MA Motlaq Evangelisches Hospital, Hattingen, Germany
Raazia Nawaz Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Maria Javed Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v72iSUPPL-2.3184

Keywords:

Meconium Stained Amniotic Fluid, membrane rupture, Meconium Aspiration Syndrome

Abstract

Objective

To determine the frequency and risk factors of meconium aspiration syndrome in babies delivered to mothers with meconium stained amniotic fluid attending neonatal unit of tertiary care hospital.

Study design

Prospective cross sectional study

Place and duration of study

Neonatal Unit “Pak Emirates Military Hospital”, Rawalpindi from 1^st January to 30^th September 2018

Patients and methods

All pregnant women with cephalic presentations with either spontaneous vaginal delivery (SVD) or lower segment cesarian section (LSCS) mode of delivery and having light-yellow to thick dark-green color liquor after spontaneous or artificial rupture of membrane were enrolled. Meconium aspiration syndrome along with risk factors like gestational age, weight, gender, mode of delivery, grades of meconium, and mortality was noted.

Results

Of 384 patients, meconium aspiration syndrome was observed in 37 (9.6%) patients. Meconium aspiration syndrome was 2.97 times higher among patients with >36 weeks of gestation (AOR: 2.97, 95% CI: 1.12-7.89), 61% higher among patients with ≤3 kg weight (AOR: 0.39, 95% CI: 0.19-0.85), 89% higher among females (AOR: 1.89, 95% CI: 0.91-3.95), 83% higher among patients with SVD (AOR: 1.83, 95% CI: 0.89-3.75), 4.12 times higher among patients with grade III (AOR: 4.12, 95% CI: 0.51-33.45) and 8.65 times higher among patients with grade II color liquor (AOR: 8.65, 95% CI: 1.11-67.45).

Conclusion

Meconium aspiration syndrome frequency was found considerably higher. In particular, newborn having higher gestational age, increased weight, female gender, SVD as the mode of delivery, grade III and grade II meconium were reported as the significant risk-factors.