ASSOCIATION OF SEROPOSITIVITY FOR CMV IGM AND IGG WITH ADVERSE PREGNANCY OUTCOME

Ambreen Amna; Farkhunda Nadeem; Amin Fahim; Altaf Hussian Jatoi; Kanwal Abbas; Sumayya Anas

doi:10.51253/pafmj.v71i3.2928

Authors

Ambreen Amna Isra University Hospital, Hyderabad Pakistan
Farkhunda Nadeem Isra University Hospital, Hyderabad Pakistan
Amin Fahim Isra University Hospital, Hyderabad Pakistan
Altaf Hussian Jatoi Mohammadi Medical College, Mirpukhas Pakistan
Kanwal Abbas Liaquat University of Medical & Sciences, Jamshora Pakistan
Sumayya Anas Isra University, Karachi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v71i3.2928

Keywords:

Adverse pregnancy outcome, Intrauterine fetal death, Preterm labour, Cytomegalovirus

Abstract

Objective: To find out the prevalence of antibodies against cytomegalovirus and their association with adverse pregnancy outcome in women, at Isra University Hospital Hyderabad.

Study Design: Cross-sectional study.

Place and Duration of Study: Department of Gynaecology & Obstetrics, Isra University Hospital (IUH) Hyderabad, from Jan to Jun 2018.

Methodology: Cytomegalovirus IgM and IgG antibodies in 305 women of reproductive age group were measured using the Enzyme Linked Fluorescent Assaysystem kit.

Results: The combined positivity of anti cytomegalovirus IgG and IgM antibodies was 93 (30.40%). About 37 (37.37%) and 28 (34.14%) women were found to be seropositive for cytomegalovirus antibodies who had history of spontaneous miscarriage and recurrent miscarriages respectively.

Conclusion: Higher association of seropositivity for cytomegalovirus IgM and IgG with bad obstetrical history and low economy was found.