Burden of Pulmonary Tuberculosis and Its Radiological Pattern, in Asymptomatic Young Males in Karachi, Pakistan

  • Huma Zaidi Pakistan Air Force Faisal Base Hospital, Karachi Pakistan
  • Haider Hussain Shah Pakistan Air Force Faisal Base Hospital, Karachi Pakistan
  • Farhan Nasrullah Pakistan Air Forces Hospital, Lahore Pakistan
  • Hussain Rashid Ihsan Pakistan Naval Ship Shifa Hospital, Karachi Pakistan
  • Muhammad Usman Khan Pakistan Naval Ship Shifa Hospital, Karachi Pakistan
Keywords: Asymptomatic, Burden, Karachi, males, Mycobacterium, Pattern, Pulmonary, Radiological, Tuberculosis

Abstract

Objective: To estimate the burden of pulmonary tuberculosis among asymptomatic young male applicants in a government organization in Pakistan and to find out the pattern of disease on chest x-ray and high-resolution CT chest.

Study Design: Prospective longitudinal study.

Place and Duration of Study: Pakistan Air Force (PAF) Faisal Base Hospital Karachi, Pakistan, from Dec 2017 to Feb 2019.

Methodology: An active search for detecting pulmonary tuberculosis was conducted in 1819 asymptomatic young male adults between 18 and 30 years who had applied for employment in a government organization with a pay scale ranging from 2 to 14 grade. Screening chest x-ray (CXR) was done as a part of their medical examination. High-resolution CT chest, sputum smear bacilloscopic and GeneXpert mycobacterium tuberculosis/resistance to Rifampicin assay tests were done in cases in which chest x-ray was suggestive of pulmonary tuberculosis.

Results: Chest x-Ray and high-resolution CT of five out of 1819 male applicants were suggestive of pulmonary tuberculosis. Three cases (0.16%) were confirmed as positive on lab tests. Radiographic and High-resolution CT patterns showed upper lobe lesions, consistent with the radiological appearance of the immuno-competent host disease.

Conclusion: The considerable presence of pulmonary tuberculosis was detected among asymptomatic young adults of this region; therefore, formulating a strategy to actively detect and treat analogous populations with high susceptibility to Pulmonary tuberculosis could help reduce this endemic disease.

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Published
2022-06-21
How to Cite
Zaidi, H., Shah, H., Nasrullah, F., Ihsan, H., & Khan, M. (2022). Burden of Pulmonary Tuberculosis and Its Radiological Pattern, in Asymptomatic Young Males in Karachi, Pakistan. Pakistan Armed Forces Medical Journal (PAFMJ), 72(3), 840-44. https://doi.org/10.51253/pafmj.v72i3.2810
Section
Original Articles