EFFECT OF AGE, GENDER AND DURATION OF DIABETES MELLITUS ON THYROID DYSFUNCTION IN PATIENTS OF DIABETIC

Kamran Ali; Sajid Ali Shah; Syed Murtaza Ali; Raja Jibran Akbar; Syed Qasim Raza; Sadia Kadir

doi:10.51253/pafmj.v71i3.2692

Authors

Kamran Ali 66 Medical Battalion, Lahore Pakistan
Sajid Ali Shah Combined Military Hospital Skardu/National University of Medical Sciences (NUMS) Pakistan
Syed Murtaza Ali Combined Military Hospital Loralae/National University of Medical Sciences (NUMS) Pakistan
Raja Jibran Akbar 123 Medical Battalion, Tolti Pakistan
Syed Qasim Raza Quaid-e-Azam International Hospital, Islamabad Pakistan
Sadia Kadir Jinnah Postgraduate Medical Centre, Karachi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v71i3.2692

Keywords:

Diabetes mellitus, Glycosylated hemoglobin, hypoglycemia, hypothyroidism, Thyroid dysfunction

Abstract

Objective: To compare the effect of age, gender and duration of diabetes mellitus on thyroid dysfunction in patients of diabetic

Study Design: Comparative cross sectional study.

Place and Duration of Study: Medicine department, Combined Military Hospital, Peshawar, from Oct 2015 to Oct 2017.

Methodology: The study was conducted after taking permission from hospital ethical review committee. Information was entered in the proforma, which included demographic information like age in years, gender, duration of disease and type of diabetes mellitus (DM) type. Already diagnosed patients with diabetes mellitus were included in the study. Thyroid function tests were carried out by standard laboratory procedure.

Results: A total of 179 patients were included in our study, 114 (63.7%) were female and 65 (36.3%) were male. Mean body mass index in our study was 29.85 ± 3.88 kg/m2. Out of 179 patients 46 (25.7%) had thyroid dysfunction (TD). Out of the 46 patients with thyroid dysfunction, 14 patients (7.8%) had clinical hypothyroidism, while subclinical hypothyroidism was seen in 25 patients (14%). Clinical hyperthyroidism was reported in 3 (1.7%), while subclinical hyperthyroidism in 4 (2.2%) patients respectively.

Conclusion: Age of patients, gender and duration of disease affect thyroid functions in patients with diabetes mellitus. Thyroid profile should be carried out in diabetic patients whose blood sugar level is difficult to control.