INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS
To assess the efficacy of intralesional bleomycin in treating plantar warts.
Study Design: Descriptive cross-sectional study.
Place and Duration of Study: Combined Military Hospital Lahore, from Jan 2015 to Sep 2015.
Material and Methods:
The study was conducted in Dermatology outpatient department, Combined Military Hospital Lahore, from Jan 2015 to Sep 2015. Total of 60 plantar warts in 20 patients were treated with 1 mg/ml intralesional injection of bleomycin. Patients received a total of four doses of bleomycin every three weeks, and were followed for next three months. We categorized the response to treatment as complete or partial resolution, and nonresponsive.
Out of 60 warts 46 warts (76.66%) showed complete resolution and 8 (13.33%) warts showed partial resolution (p<0.001). The cure rate was better in warts smaller than 20 mm in diameter in comparison with larger lesions. After six months follow-up, 3 (15%) of the completely resolved warts showed recurrence. Recurrence was more among those with greater number of warts.
Intralesional bleomycin injections were found to be a reliable, safe and acceptable mode of treatment for plantar warts.