ROLE OF SIGNAL DOSE PREOPERATIVE ANTIBIOTIC IN ACUTE NONPERFORATED APPENDICITICS

Acute Nonperforated Appendicitics

Authors

  • Dr Saad Ahmed Malik Surgical Specialist, 32 (1) MST
  • Misbah Rasheed . Combined Military Hospital Lahore
  • Amjad Saeed Abbasi Combined Military Hospital Rawalpindi
  • Raja Azhar Iqbal Combined Military Hospital Rawalpindi
  • Muhammad Amir Mian Combined Military Hospital Rawalpindi

Keywords:

Appendicectomy, Acute appendicitis and Cefuroxime

Abstract

Objective: To determine the efficacy of a single dose of preoperative antibiotic in preventing post operative infective complications in patients undergoing appendicectomy for non perforated acute appendicitis.
Study Design: Randomized controlled trials.
Place and Duration of Study: Surgical unit I and II, department of General Surgery, Combined Military Hospital (CMH) Lahore from 1st June to 31st October 2010.
Patients and Methods: Seventy patients with acute appendicitis scheduled for appendicectomy were included in the study and randomly divided into two groups of 35 each using random numbers table. Group A received single dose preoperative antibiotic and group B received three-dose regimens of cefuroxime. Postoperative infective complications were the primary endpoint.
Results: The rate of postoperative wound infection was not statistically insignificantly different among the groups; (8.57%) group A and (5.71%) group B at 1st post operative week and (5.71%) group A and (5.71%) group B at 2nd post operative week. None of the patients from either group showed any signs of intra abdominal abscess formation.
Conclusion: Single dose of preoperative antibiotics is adequate for prevention of postoperative infective complications in patients with non-perforated appendicitis undergoing open appendicectomy.

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Published

31-03-2013

How to Cite

Malik, D. S. A., ., M. R., Abbasi, A. S., Iqbal, R. A., & Mian, M. A. (2013). ROLE OF SIGNAL DOSE PREOPERATIVE ANTIBIOTIC IN ACUTE NONPERFORATED APPENDICITICS: Acute Nonperforated Appendicitics. Pakistan Armed Forces Medical Journal, 63(1), 114–117. Retrieved from https://pafmj.org/PAFMJ/article/view/2183

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Original Articles

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