THE EFFECT OF OLIVE-POMACE OIL ON DIFFERENT BLOOD PARAMETERS IN STREPTOZOTOCIN INDUCED DIABETIC RATS

Effect of Olive-Pomace Oil on Blood Parameters in Rats

Authors

  • Abdul Khaliq Naveed Army Medical College, National University of Sciences and Technology (NUST), Islamabad
  • Muhammad Javad Yousaf Army Medical College, National University of Sciences and Technology (NUST), Islamabad
  • Shakir Khan Army Medical College, National University of Sciences and Technology (NUST), Islamabad
  • Tausif Ahmed Army Medical College, National University of Sciences and Technology (NUST), Islamabad
  • Syed Zubair Hussain Shah Army Medical College, National University of Sciences and Technology (NUST), Islamabad

Keywords:

Diabetes mellitus, Dyslipidemia, Hyperglycemia, Olive pomace oil

Abstract

Objective: To determine the effects of olive-pomace oil on glycemic status and lipid profile in diabetes.
Study Design: Randomized controlled trial.
Place and Duration of Study: Department of Biochemistry, Army Medical College, Rawalpindi in collaboration with Centre for Research in Experimental and Applied Medicine, Army Medical College, Rawalpindi and National Institute of Health, Islamabad from March 2010 to June 2011.
Material and Methods: Seventy male albino rats of Sprague-Dawley strain were randomly divided into two groups of 35 rats each. Rats were rendered diabetic by injecting streptozotocin. Group 1 and group 2 were given normal rodent diet and olive pomace oil supplemented diet respectively for 6 weeks. At the end of the experiment fasting blood glucose and lipid profile were measured for comparison.
Results: There was significant increase in high density lipoprotein and significant decrease of blood glucose, total cholesterol and low density lipoprotein of group II rats when compared with group I (control).
Conclusion: Olive pomace oil can significantly improve fasting blood glucose and lipid profile in diabetic rats.

 

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Published

30-09-2014

Issue

Vol. 64 No. 3 (2014): September

Section

Original Articles

How to Cite

1.
Naveed AK, Yousaf MJ, Khan S, Ahmed T, Shah SZH. THE EFFECT OF OLIVE-POMACE OIL ON DIFFERENT BLOOD PARAMETERS IN STREPTOZOTOCIN INDUCED DIABETIC RATS: Effect of Olive-Pomace Oil on Blood Parameters in Rats. Pak Armed Forces Med J [Internet]. 2014 Sep. 30 [cited 2024 Dec. 21];64(3):443-6. Available from: https://pafmj.org/PAFMJ/article/view/1313