PSORIASIS AREA SEVERITY INDEX (PASI) AND THE DERMATOLOGY LIFE QUALITY INDEX (DLQI): THE CORRELATION BETWEEN DISEASE SEVERITY AND QUALITY OF LIFE IN PATIENTS OF PSORIASIS
PASI And DLQI in Patients of Psoriasis
Objective: To determine the correlation between Psoriasis Area Severity Index (PASI) and Dermatology Life Quality Index (DLQI) in patients of psoriasis.
Study Design: Cross sectional study.
Place and Duration of Study: Both outdoor and indoor patients of Dermatology Department, Military Hospital (MH) Rawalpindi for duration of 6 months i.e. from 6th Oct 2014 to 5th Apr 2014 were selected.
Material and Methods: A total of 155 patients of chronic plaque psoriasis diagnosed clinically, ranging from 20 to 80 years of age and of either gender were included in the study. A careful history and clinical examination was done and for each case PASI and DLQI were calculated and registered in the designed proforma. Data were entered and analyzed in SPSS version-17.0. Mean and standard deviations were calculated for quantitative variables like age, PASI and DLQI. Frequencies and percentages were calculated for qualitative variables like gender. Pearson’s correlation coefficient (r) (+1,-1) was calculated between mean PASI and mean DLQI. A p-value <0.05 was considered as significant. Stratification was done for age and gender and post stratification correlation was calculated.
Results: Out of 155 patients studied, 110 (70.97%) were males and 45 (29.03%) were females. Ages of the patients ranged from 20-80 years (mean age 49.5 ± 15.6 years). Mean PASI score was 27.92 ± 5.83 and DLQ1 was 11.46 ± 4.22. The value of Pearson correlation coefficient (r) was 0.1324 which showed weak correlation between PASI and DLQ1 with p-value of 0.100. Weak correlation (r=-0.3394) in age 51-80 years while very weak correlation (r=-0.0651) in age 20-50 years was noted. PASI and DLQ1 showed weak correlation in males (r=0.132) and in females (r=0.461).
Conclusion: This study concluded that there is a weak correlation between PASI and DLQI.