TY - JOUR AU - Zubair, Muhammad AU - Afridi, Nabeel Khan AU - Nawaid, Muhammad Amir AU - Tariq, Hassan AU - Bajwa, Akhter Ali AU - Khan, Naveed PY - 2022/12/29 Y2 - 2024/03/29 TI - Histopathological Analysis of Gastric Biopsies using Updated Sydney System JF - Pakistan Armed Forces Medical Journal JA - PAFMJ VL - 72 IS - 6 SE - Original Articles DO - 10.51253/pafmj.v72i6.6458 UR - https://pafmj.org/PAFMJ/article/view/6458 SP - 1969-72 AB - <p><strong>Objective:</strong> To analyse histopathological findings in gastric biopsies of patients with dyspepsia using an updated Sydney System.</p><p><strong>Study Design:</strong> Retrospective longitudinal study.</p><p><strong>Place and Duration of Study:</strong> Histopathology Department, Najran Armed Forces Hospital (NAFH), Saudi Arabia, from Jan 2013 to Mar 2020.</p><p><strong>Methodology:</strong> A total of 408 cases whose gastric biopsies were included in the study, and their histological features were studied.</p><p><strong>Results:</strong> Among 408 patients included in the study, 191(46.8%) were males, and 217(53.2%) were females. The mean age was 37.0±15.0 years. A total of 343 patients showed gastritis, which was mild 152(44.3%), moderate 158(46.1%) and severe 33(9.6%), respectively. The activity was observed in 200(49.0%) patients. H.pylori infection was observed in 196(48.0%) patients and intestinal metaplasia in 9(2.2%) patients. </p><p><strong>Conclusion:</strong> Most of the cases with dyspepsia showed histological evidence of gastritis. However, a significant number of patients had no gastric mucosal abnormality. Therefore, adequate and timely treatment of H.pylori infection can significantly reduce related morbidity.</p> ER -