TY - JOUR AU - Iqbal, Nazia AU - Muzaffar, Waqar AU - Sarfaraz, Muhammad Haroon AU - Khan, Saim AU - Yasin, Ubaid Ullah AU - Abidin, Farooq Ul PY - 2022/03/01 Y2 - 2024/03/29 TI - Efficacy of Timolol Maleate (0.5%) in Preventing Rise of Intraocular Pressure (IOP) Post Neodymium: Yttrium Aluminum Garnet (Nd: YAG) Capsulotomy JF - Pakistan Armed Forces Medical Journal JA - PAFMJ VL - 72 IS - 1 SE - Original Articles DO - 10.51253/pafmj.v72i1.6219 UR - https://pafmj.org/PAFMJ/article/view/6219 SP - 255-59 AB - <p><strong>Objective:</strong> To determine the efficacy of 0.5% Timolol eye drops in preventing rise of intraocular pressure following Neodymium: Yttrium-Aluminum-Garnet laser posterior capsulotomy.</p><p><strong>Study Design:</strong> Quasi-experimental study.</p><p><strong>Place and Duration of Study:</strong> Outpatient Department of Ophthalmology, Combined Military Hospital Multan Pakistan, from May to Nov 2019.</p><p><strong>Methodology:</strong> Patients presenting with posterior capsule opacification, undergoing elective Neodymium: Yttrium Aluminum Garnet (Nd: Yag) Capsulotomy were enrolled in the study. Patients were alternatively assigned to two groups; group-1 was administered 0.5% Timolol Maleate eye drops, while group-2 was administered placebo natural team eye drops. Intraocular pressure for all the patients was measured at three-time points a). First measurement was baseline intraocular pressure at presentation/before the treatment. Second measurement was 1-hour post laser capsulotomy and third measurement was 3 hours post laser capsulotomy.</p><p><strong>Results:</strong> At 1-hour follow up, the mean intraocular pressure was significantly raised in the patients belonging to control group as compared to treatment group (21.45 ± 8.33 mm Hg vs 15.33 ± 3.37 mm Hg, p&lt;0.001). At 3-hours follow-up the mean intraocular pressure decreased a bit for control group but still was significantly higher than the treatment group (17.40 ± 3.00 mm Hg vs 15.60 ± 2.30 mm Hg, p&lt;0.001).</p><p><strong>Conclusion:</strong> Prophylactic use of Timolol successfully reduces the post-procedural acute rise in intraocular pressure due to Neodymium: Yttrium Aluminum Garnet laser posterior capsulotomy.</p> ER -