TY - JOUR AU - Abbas, Ghulam AU - Sheraz, Atif AU - Rahim, Raza PY - 2021/06/30 Y2 - 2024/03/28 TI - EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMA JF - Pakistan Armed Forces Medical Journal JA - PAFMJ VL - 71 IS - 3 SE - Original Articles DO - 10.51253/pafmj.v71i3.4843 UR - https://pafmj.org/PAFMJ/article/view/4843 SP - 910-15 AB - <p><strong>Objective:</strong> To assess the efficacy of intra-arterial lidocaine in peri &amp; post-procedural pain control and the dose of narcotic analgesic required in hepatocellular carcinoma patients undergoing transarterial chemoembolization.</p><p><strong>Study Design:</strong> Comparative prospective study.</p><p><strong>Place and Duration of Study:</strong> Armed Forces Institute of Radiology and Imaging Rawalpindi, from Jan to Jun 2019.</p><p><strong>Methodology:</strong> A total of 60 patients included in this study where 42 males and 18 were females, age range 45-85 years who underwent transarterial chemoembolization for hepatocellular carcinoma, were included in the study. patients were equally divided into two groups, group a (30 patients) who underwent transarterial chemoembolization, received 60 mg of intraarterial lidocaine each and group b (30 patients) who underwent transarterial chemoembolization, intra-arterial lidocaine was substituted with normal saline.degree of post-procedural pain was assessed using a subjective method (visual analogue scales score) and an objective method (amount of post-procedural analgesics).</p><p><strong>Results:</strong> Average peri-procedure visual analogue scale score was 5.06 in group A patient versus 7.2 for those in group B patients (p=0.037). Post-procedure visual analogue scale score in the group A was 2.7 ± 0.520 and that for group B was 4.2 ± 0.761 (p=0.025). Mean of total dose of nalbuphine in group A was 4.96 ± 0.764 mg versus 8.3 ± 1.34 mg for patients in group B (p=0.036). Average length of post procedure hospital stay was 0.9 ± 0.203 and 1.41 ± 0.373 days for group A and group B respectively (p=0.002).<br><strong>Conclusion:</strong> Intra-arterial administration of lidocaine before infusing the embolization particles for transarterial chemoembolization.....................<br><br></p> ER -