TY - JOUR AU - Naeem, Fizza AU - Raza, Sayed Nusrat AU - Khan, Taimoor Ashraf PY - 2021/02/23 Y2 - 2024/03/28 TI - MALIGNANCY IN MULTINODULAR GOITER-POST THYROIDECTOMY: A PROSPECTIVE STUDY JF - Pakistan Armed Forces Medical Journal JA - PAFMJ VL - 71 IS - 1 SE - Original Articles DO - 10.51253/pafmj.v71i1.4653 UR - https://pafmj.org/PAFMJ/article/view/4653 SP - 3-6 AB - <p><strong>Objective:</strong> To find out the frequency and types of malignancy in patients treated surgically for nontoxic<br>multinodular goiter and its correlation in different age groups and gender.</p><p><strong>Study Design:</strong> Cross-sectional study.</p><p><strong>Place and Duration of Study:</strong> Department of ENT, Combined Military Hospital Rawalpindi, from Dec 2018 to<br>Dec 2019.</p><p><strong>Methodology:</strong> A total of 116 patients operated for nontoxic multinodular goiter were included in the study.<br>Demographic details along with pre-op Ultrasonography findings, Fine Needle Aspiration Cytology, thyroid<br>function test results and post-op histopathological reports of the thyroid specimen were entered on pre-designed proforma. Results were analyzed using the Statistical Package for Social Sciences (SPSS) Version 22.</p><p><strong>Results:</strong> Age ranges from 19 to 70 years (mean 43.51 years). Out of 116 cases operated for multinodular goiter,<br>37 (31.8%) had malignant thyroid lesions (13 males, 24 females). Papillary carcinoma of the thyroid (45.9%) was<br>the commonest malignancy followed by a follicular variant of papillary carcinoma (24.3%). The most common age group with malignancies was 49-58 years.</p><p><strong>Conclusion:</strong> Malignant Thyroid cancers showed a female preponderance and were most common in age group<br>49-58 years. Papillary carcinoma of thyroid was the commonest tumor. Radical thyroid surgery is a recommended surgical management option for nontoxic Multinodular goiter.</p> ER -