TY - JOUR AU - Jabbar, Bushra AU - Islam, Qamar Ul AU - Hanif, Muhammad Kashif AU - Yasin, Ubaidullah AU - Farooq, Omer AU - Fatima, Saman PY - 2020/12/16 Y2 - 2024/03/29 TI - SHORT TERM EFFECT OF HEMODIALYSIS ON PERIPAPILLARY RETINAL NERVE FIBER LAYER AND MACULAR THICKNESS JF - Pakistan Armed Forces Medical Journal JA - PAFMJ VL - 70 IS - 6 SE - Original Articles DO - 10.51253/pafmj.v70i6.4040 UR - https://pafmj.org/PAFMJ/article/view/4040 SP - 1804-09 AB - <p><strong>Objective:</strong> To determine the thicknesses of retinal nerve fiber layer (RNFL) and macula by fourier-domain (FD)<br>optical coherence tomography (OCT) in diabetic patients with end-stage renal failure (ESRF) undergoing<br>hemodialysis.</p><p><strong>Study Design:</strong> Cross-sectional study.</p><p><strong>Place and Duration of Study:</strong> Pakistan Naval Ship, Shifa Karachi, from Jan 2019 to Jul 2019</p><p><strong>Methodology:</strong> Fifty four patients presenting to nephrology department who met the inclusion criteria were<br>included in the study. Macular and retinal nerve fibre layer thicknesses were compared pre and post 30 minutes<br>of hemodialysis and their correlation (r=-0.89) with age, duration of hemodialysis and gender was examined. Pre hemodialysis temporal, inferior, average retinal nerve fibre layer thicknesses were observed thinner than Post hemodialysis.</p><p><strong>Results: </strong>Pre-hemodialysis macular thicknesses were thinner than post hemodialysis. Thinning of Macular and<br>RNFL showed a negative relationship with age and duration of hemodialysis (r=-0.89 &amp; -0.76). Temporal, superior quadrants and average retinal nerve fiber layer thickness values were found statistically different in pre and post 30 minutes hemodialysis examination (p-value = 0.002, 0.001 &amp; 0.0021) while, nasal and inferior quadrants were found statistically insignificant. Whereas in macula, temporal and superior quadrants were found statistically significant (p-value=0.005 &amp; 0.002) and nasal, Inferior and average thickness were found statistically insignificant (p-value = 0.0641, 0.0594 &amp; 0.083).</p><p><strong>Conclusion:</strong> Macular and retinal nerve fiber layer thicknesses of patients receiving hemodialysis were less<br>than the normal population. Age has no effect on these thinning. The duration of hemodialysis effects more than gender. Hemodialysis session causes a consistent............. </p> ER -