TY - JOUR AU - Kazmi, Syed Sakhawat AU - Alamgir, Waseem AU - Hashmat, Asif AU - Yousaf, Ali AU - Nawaz, Khurram Haq AU - Hassan, Zahid PY - 2022/06/08 Y2 - 2024/03/29 TI - Plasmapheresis in Neurological Disorders: Frequency and Type of Adverse Effects Associated with this Procedure in Atertiary Care Hospital in Pakistan JF - Pakistan Armed Forces Medical Journal JA - PAFMJ VL - 72 IS - SUPPL-2 SE - Original Articles DO - 10.51253/pafmj.v72iSUPPL-2.3865 UR - https://pafmj.org/PAFMJ/article/view/3865 SP - S389-92 AB - <p><strong>Objective:</strong> To determine the frequency and type of adverse effects associated with plasmapheresis among the patients with neurological disorders at a tertiary care hospital in Pakistan.</p><p><strong>Study Design:</strong> Prospective longitudinal study.</p><p><strong>Place and Duration of Study:</strong> Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan to Jun 2019.</p><p><strong>Methodology:</strong> The sample population comprised 150 patients with various neurological disorders requiring plasmapheresis at a tertiary care hospital in Rawalpindi, Pakistan. The consultant neuro physician diagnosed the underlying disorder, and a management plan of plasmapheresis was given after the departmental meeting. The presence of adverse effects was observed during the session of plasmapheresis till 48 hours after the session.</p><p><strong>Results:</strong> Out of 150 patients with neurological illness undergoing plasmapheresis at our department, 18 (12%) developed one or more adverse effects due to the procedure, while 132 (88%) did not experience any adverse effects. The mean age of the patients was 30.2 ± 2.698 years. GB syndrome 61 (40.6%) was the commonest disease for which plasmapheresis was done. Allergic reaction 4 (2.6%) was the commonest side effect among the patients undergoing plasmapheresis, followed by abdominal pain 3 (2%). 146 (97.4%) patients were shifted toward, and 4 (2.6%) required intensive care unit admission after the procedure due to complications. Mortality due to this procedure was nil in the given period.</p><p><strong>Conclusion:</strong> Plasmapheresis is a relatively safe procedure for neurological illnesses with an immunological basis. Patients should be told about the common adverse effects they could face during the procedure especially allergic reactions and...</p> ER -