TY - JOUR AU - Mirza, Rabbia AU - Basit, Imran AU - Khan, Summaya AU - Ullah, Zahid AU - Tarar, Shahid AU - Awais, Muhammad PY - 2021/08/27 Y2 - 2024/03/28 TI - INHIBITION OF SURGICALLY INDUCED MIOSIS WITH NEPAFENAC JF - Pakistan Armed Forces Medical Journal JA - PAFMJ VL - 71 IS - 4 SE - Original Articles DO - 10.51253/pafmj.v71i3.3324 UR - https://pafmj.org/PAFMJ/article/view/3324 SP - 1451-54 AB - <p><strong>Objective:</strong> To assess the efficacy of prophylactic administration of 0.1% nepafenac in the maintenance of trans-operative mydriasis following cataract surgery.</p><p><strong>Study Design:</strong> Quasi-experimental study.</p><p><strong>Place and Duration of Study:</strong> Armed Forces Institute of Ophthalmology, Rawalpindi, from Oct 2018 to Mar 2019.</p><p><strong>Methodology:</strong> A total of 70 patients undergoing cataract surgery phacoemulsification were randomly placed in either the control group or the nepafenac group. Nepafenac eye drops were administered as one drop 8 hourly, 3 days before surgery. Control group didn’t receive any medication preoperatively Mydriasis was measured trans-operatively before surgery, after aspiration of the cortex, and then at the end of surgery. Patients of both groups received tobradex 2 weeks post-surgery.</p><p><strong>Results:</strong> Post-surgery statistically significant (0.001) difference was observed in the mean pupil size between the nepafenac group (7.88 ± 0.49) and the control group (6.57 ± 0.92 mm).</p><p><strong>Conclusion:</strong> Use of nepafenac prophylactically was very effective in maintenance of trans-operative mydriasis in cataract surgery.</p> ER -