TY - JOUR AU - Ahmed, Naveed AU - Ahmad, Fawad AU - Soomro, Irfan Ali AU - Yusuf, Muhammad Ali PY - 2018/10/30 Y2 - 2024/03/29 TI - FREQUENCY OF PROLONGED CORRECTED QT INTERVAL IN CHILD PUGH CLASS IN PATIENTS OF CIRRHOSIS OF LIVER: Child Pugh Class of Cirrhosis of Liver JF - Pakistan Armed Forces Medical Journal JA - PAFMJ VL - 68 IS - 3 SE - Original Articles DO - UR - https://pafmj.org/PAFMJ/article/view/261 SP - 475-78 AB - <p><strong>Objective:</strong>&nbsp;To determine the frequency of prolonged corrected QT interval (QTc) in Child Pugh Class in patients of liver cirrhosis presenting to Combined Military Hospital Peshawar. Study&nbsp;<strong>Design:</strong>&nbsp;Cross sectional study. Place and Duration of Study: Department of Medicine, Combined Military Hospital Peshawar, from Dec 2013 to Jun 2014. Material and Methods: One hundred and thirty three patients with liver cirrhosis fulfilling the inclusion criteria were included in the study using non-probability consecutive sampling after taking informed consent. All patients were assigned their Child’s Class either A, B or C. Electrocardiogram (ECG) was done and QTc was calculated using Bazett’s formula. QTc of more than 0.44 seconds was taken as prolonged.&nbsp;<strong>Results:</strong>&nbsp;Out of 133 patients, QTc was prolonged in 78 patients yielding frequency of QTc prolongation in cirrhosis of 58.64%. Frequency of QTc prolongation was 61.18% in males and 54.17% in females. QTc prolongation was 15% in Child Pugh grade A, 54.76% in Child Pugh grade B and 73.24% in Child Pugh grade C. There was a statistically significant association between QTc prolongation and the severity of cirrhosis (p&lt;0.001). Conclusion: This study concludes that there was a statistically significant increase in frequency of QTc prolongation with worsening of Child Pugh Class thereby indicating an association between QTc prolongation and the severity of cirrhosis.</p> ER -