@article{Munir_Aamir_Haroon_Kirmani_Yasir_Habib_2023, title={A Survey of Growth Hormone Stimulation Test Efficacy for Workup of Short Stature in a Referral Laboratory}, volume={73}, url={https://pafmj.org/PAFMJ/article/view/7906}, DOI={10.51253/pafmj.v73i2.7906}, abstractNote={<p><strong>Objective:</strong> To assess growth hormone (GH) stimulation test efficacy in short stature workup for establishing GH deficiency.</p> <p><strong>Study Design:</strong> Cross-sectional survey.</p> <p><strong> Place and Duration of Study:</strong> Diagnostic Endocrine Section, Department of Chemical Pathology & Endocrinology, Armed Forces Institute of Pathology (AFIP), Rawalpindi Pakistan, from Aug 2020 to Jan 2021.</p> <p><strong> Methodology:</strong> The study was conducted on 129 individuals aged 2-16 years. History, axiological data and biochemical parameters were assessed to establish GH deficiency for short stature workup.</p> <p><strong> Results:</strong> Out of 129 individuals, 76(59%) boys and 53(41%) girls reported GH stimulation tests. 81(62.3%) children were in <3rd percentile, 29(22.3%) in <5th percentile, 9(6.9%) in <10th percentile and 5(3.8%) in <25th percentile. Among the group with bone age difference >2 years, 34(82.9%) fell in <3rd percentile. GH Stimulation test post-Levo Dopa was performed in 102(78.46%) patients. 49(37.4%) patients responded inadequately to the GH stimulation test. The adequate response to the GH Stimulation test improved as the percentile declined from the 50th to the 3rd percentile.</p> <p><strong>Conclusion:</strong> GH stimulation test results can only partially rely upon though their importance remains in combination with other short-stature workup parameters for ruling out growth hormone deficiency. </p>}, number={2}, journal={Pakistan Armed Forces Medical Journal}, author={Munir, Muhammad Usman and Aamir, Muhammad and Haroon, Zujaja Hina and Kirmani, Sobia Irum and Yasir, Afshan and Habib, Hunain}, year={2023}, month={Apr.}, pages={477–80} }