@article{Arshad_Humayun_Kamran_Ifikhar_Yousaf_Sajid_2022, title={Role of Methylprednisolone for Covid-19 Patients Admitted to a Tertiary Care Hospital}, volume={72}, url={https://pafmj.org/PAFMJ/article/view/6602}, DOI={10.51253/pafmj.v72i6.6602}, abstractNote={<p><strong>Objective:</strong> To determine the role of Methylprednisolone in managing COVID-19 patients.</p> <p><strong>Study Design:</strong> Cross-sectional study.</p> <p><strong>Place and Duration of Study:</strong> Pakistan Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Jan to Feb 2021.</p> <p><strong>Methodology:</strong> This study was carried out at the Department of Medicine. Medical records of all moderate, severe and critical COVID-19 patients admitted and receiving Methylprednisolone were reviewed. Methylprednisolone was used in all patients at doses 0.-2 mg per kg.</p> <p><strong>Results:</strong> A total of 200 cases were included. The most common presenting symptoms were cough (77.5%), fever (67.5%) and shortness of breath (63.5%). Most patients (85%) presented within the first week of their illness. One or more comorbidities were present in 75% of patients. Most common being hypertension in 70(35%) and diabetes mellitus in 63(31.5%).Complications seen in the study were Cytokine release storm 92(46%) and acute respiratory distress syndrome 44(22%). The median time for initiation of corticosteroid therapy was 4 hours (range 1-96 hours). Overall survival (OS) in the study was 83.5%. OS for patients with moderate, severe and critical diseases was 97.8%, 86.2% and 62%, respectively (p<0.001).<br><strong>Conclusion:</strong> Corticosteroids are useful in COVID-19-admitted patients and provide excellent survival outcomes.<br>Keywords: Acute respiratory distress syndrome, COVID-19, Cytokine release storm, Methylprednisolone.</p>}, number={6}, journal={Pakistan Armed Forces Medical Journal}, author={Arshad, Komal and Humayun, Zill e and Kamran, Sultan Mehmood and Ifikhar, Raheel and Yousaf, Ali and Sajid, Muhammad Usman}, year={2022}, month={Dec.}, pages={2041–44} }