@article{Tariq_Janjua_Mehmood_Khalid_Zafar_Hameed_2021, title={COMPARISON OF EFFECTIVENESS OF CARBAMAZEPINE VERSUS TOPIRAMATE FOR THE MANAGEMENT OF TRIGEMINAL NEURALGIA}, volume={71}, url={https://pafmj.org/PAFMJ/article/view/6083}, DOI={10.51253/pafmj.v71i4.6083}, abstractNote={<p><strong>Objective:</strong> To compare the effectiveness of Carbamazepine versus Topiramate for the management of trigeminal neuralgia.</p> <p><strong>Study Design:</strong> Comparative prospective study.</p> <p><strong>Place and Duration of Study:</strong> Oral and Maxillofacial Surgery department, Allied Hospital, Faisalabad Pakistan, from Nov 2017 to Nov 2018.</p> <p><strong>Methodology:</strong> A total of 60 patients (30 in each group) were included. Group A was treated with Carbamazepine 100mg TDS and group B with Topiramate 25mg TDS. Visual analogue scale was used to access pain and was calculated at 1st visit (baseline), at 7th day, at 14th day and at 28th day.</p> <p><strong>Results:</strong> Out of 60 patients, mean of age was 54.78 ± 8.49 years. Right and left side of the face was involved in 41 (68.3%) and 19 (31.7%) patients respectively. Maxillary branch was involved in 24 (40%) and mandibular branch was involved in 36 (60%) patients. The mean of visual analogue scale after 7 days in group A was 4.53 ± 0.93 and in group B was 7.1 ± 1.07, after 14 days mean of visual analogue scale in group A was 3.7 ± 1.02 and in group B was 4.03 ± 1.27. Mean of visual analogue scale after 28 days in group A was 3.27 ± 1.01 3.93 ± 1.28. The results were statistically significant with p-value of 0.03.</p> <p><strong>Conclusion:</strong> Topiramate has comparable efficacy as that of Carbamazepine at dose of 75-100mg with lesser side effects. So Topiramate can be used as first line of treatment in trigeminal neuralgia.</p>}, number={4}, journal={Pakistan Armed Forces Medical Journal}, author={Tariq, Ramish and Janjua, Omer Sefvan and Mehmood, Sana and Khalid, Muhammad Usman and Zafar, Khurram Jah and Hameed, Saad}, year={2021}, month={Aug.}, pages={1360–63} }