@article{Qurni_Tariq_Tahir_Din_Mansur_Nadeem_2021, title={FREQUENCY OF PEDIATRIC BRAIN TUMORS IN TERTIARY CARE INSTITUTE OF PAKISTAN AND COMPARISON WITH INTERNATIONAL DATA}, volume={71}, url={https://pafmj.org/PAFMJ/article/view/5479}, DOI={10.51253/pafmj.v71i3.5479}, abstractNote={<p><strong>Objective:</strong> To analyze the histological spectrum of pediatric brain tumors (PBT) in Pakistani population and to compare the results with international data.</p> <p><strong>Study Design:</strong> Retrospective observational study.</p> <p><strong>Place and Duration of Study:</strong> Armed Forces Institute of Pathology, Rawalpindi, from Jan 2015 and Dec 2019.</p> <p><strong>Methodology:</strong> This data was analyzed using the latest World Health Organization (WHO) classification of Tumors of Central Nervous System 2016. The cases were divided in 5 categories according to age (0-2, 3-5, 6-8, 9-11 & 12-14 years).</p> <p><strong>Results:</strong> A total of 43 cases were included in the study. Of these cases, 26 (60.46%) were male and 17 (39.5%) were female. Male to female ratio was 1.5-1. The 6-8 year age group had the highest number of tumors while 0-2 year age group had the least. Mean age of diagnosis was 7.6 years. Ependymoma wasthe most common morphological type with 12 cases (28%) followed by pilocytic astrocytoma, diffuse glioma with 10 cases each (23%) and medulloblastoma with 9 cases (21%). Least common tumor subtype was Ewing sarcoma. Ependymoma were mostly of grade 3 (64%), pilocytic astrocytoma and medulloblastoma were of grade 1 and grade 4 respectively by definition, and diffuse gliomas were mainly of grade 2 (57%) type.</p> <p><strong>Conclusion:</strong> Ependymoma and pilocytic astrocytomaare the most frequent types of pediatric brain tumors in our region which follows the same trend as mentioned in western and regional literature.</p>}, number={3}, journal={Pakistan Armed Forces Medical Journal}, author={Qurni, Muhammad Owais and Tariq, Hassan and Tahir, Hiba and Din, Hafeez Ud and Mansur, Hamza and Nadeem, Maria}, year={2021}, month={Jun.}, pages={989–92} }