@article{Rizwan_Raza_Anwar_Khokhar_2021, title={COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR}, volume={71}, url={https://pafmj.org/PAFMJ/article/view/4555}, DOI={10.51253/pafmj.v71iSuppl-1.4555}, abstractNote={<p><strong>Objective:</strong> To compare the efficacy of oral fluconazole and oral itraconazole in the treatment of Pityriasis<br>versicolor.</p> <p><strong>Study Design:</strong> Comparative prospective study.</p> <p><strong>Methodology:</strong> Total 72 patients of both genders with Pityriasis versicolor were included. Patients were randomly allocated into two treatment groups with 36 patients in each group: group A and group B by lottery method. Patients in group A received Cap Fluconazole 150 mg bi- weekly for two consecutive weeks while those in group B received two doses of 400 mg of itraconazole once weekly for two weeks. Patients were asked to follow-up after 4 weeks skin scrapings for microscopy using 10% KOH mount was done at follow-up. Efficacy was assessed in terms of negative fungal hyphae on microscopy.</p> <p><strong>Results:</strong> In this study, age ranged from 18 to 40 years with mean age of 33.52 ± 4.12 years in group A, whereas<br>35.055 ± 4.18 years in group B. Mean duration of disease was 4.66 ± 1.51 months in group A and 5.27 ± 1.70<br>months in group B. Efficacy was seen in 77.8% of group A patients as compared to 50% in group B patients<br>(p=0.014).</p> <p><strong>Conclusion:</strong> Oral Fluconazole two doses of 150 mg/week (total 300mg/week) for two consecutive weeks was<br>found more effective than oral itraconazole.</p>}, number={Suppl-1}, journal={Pakistan Armed Forces Medical Journal}, author={Rizwan, Muhammad and Raza, Naeem and Anwar, Ayesha and Khokhar, Ayesha}, year={2021}, month={Feb.}, pages={S273–76} }