@article{Kashif_Kundi_Khan_2021, title={PRE-EMPTIVE EFFECT OF INTRAVENOUS PARACETAMOL VERSUS INTRAVENOUS KETOROLAC ON POST-OPERATIVE PAIN AND SHIVERING AFTER SEPTOPLASTY UNDER GENERAL ANESTHESIA: A COMPARATIVE STUDY}, volume={71}, url={https://pafmj.org/PAFMJ/article/view/4269}, DOI={10.51253/pafmj.v71i4.4269}, abstractNote={<p><strong>Objective:</strong> To observe the pre-emptive effect of intravenous paracetamol versus intravenous ketorolac in preventing postoperative shivering and pain after septoplasty in postoperative care unit.</p> <p><strong>Study Design:</strong> Prospective comparative study.</p> <p><strong>Place and Duration of Study:</strong> Main Operation Theatre of Frontier Corps Hospital Quetta, from Sep to Dec 2019.</p> <p><strong>Methodology:</strong> After ethical committee approval, 90 American Society of Anaesthesiologist (ASA-I patients, aged between 18-45 years, scheduled for septoplasty, were recruited and divided into three equal groups, Paracetamol (PA), Ketorolac (KE) and Placebo (PL) as per computer generated table. The paracetamol (PA) group (n=30) received 1gm intravenous paracetamol, ketorolac (KE) group (n=30) received 30mg intravenous ketorolac and group placebo (PL) received 100ml normal saline, 20 minutes before completion of surgery. Postoperative shivering and pain was assessed via four-point scale and visual analogue scale (VAS) respectively, in post-anesthesia care unit at 10 and 30 minutes post-extubation.</p> <p><strong>Results:</strong> Mean visual analog scale (VAS) score in paracetamol group was 2.7 ± 1.41, ketorolac group was 2.3 ± 1.24 and in placebo group was 3.6 ± 1.44, with a p-value of 0.002. Mean four point shivering score in paracetamol group was 0.3 ± 0.55, ketorolac was 0.7 ± 0.78 and placebo group was 1.4 ± 1.00, with a p-value of <0.001.</p> <p><strong>Conclusion:</strong> The effect of paracetamol is better than ketorolac in preventing pain and shivering after septoplasty under general anesthesia.</p>}, number={4}, journal={Pakistan Armed Forces Medical Journal}, author={Kashif, Sanum and Kundi, M Nasir and Khan, Taimur Azam}, year={2021}, month={Aug.}, pages={1179–82} }