@article{Ahmed_Niazi_Shah_Khan_Bukhsh_Ashraf_2021, title={EVALUATION OF PERIPAPILLARY RETINAL NERVE FIBRE LAYER AND CENTRAL MACULAR THICKNESS INADULTS WITH HYPEROPIC ANISOMETROPIC AMBLYOPIA}, volume={71}, url={https://pafmj.org/PAFMJ/article/view/3975}, DOI={10.51253/pafmj.v71i1.3975}, abstractNote={<p><strong>Objective:</strong> To study per-papillary retinal nerve fibre layer (pRNFL) and central macular thickness (CMT) changes<br>in adults with hyperopic anisometropic amblyopia using optical coherence tomography.</p> <p><strong>Study Design:</strong> Cross sectional study.</p> <p><strong>Place and Duration of Study:</strong> Combined Military Hospital, Lahore, Pakistan, from Oct 2019 to Feb 2020.</p> <p><strong>Methodology:</strong> In this study 30 adults, 18-40 years of age were included who presented in our clinic with monocular poor vision. They underwent detailed ophthalmic clinical examination: including corrected and uncorrected distance visual acuity, slit lamp bio-microscopy and fundus examination with 90 diopter lens. After fulfilling criteria of anisometropic amblyopia, central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness was measured by using RS-3000 SLO, NIDEK Co, Japan spectral domain optical coherence tomography device and compared the central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic and fellow eye of same individual.</p> <p><strong>Results:</strong> The mean change in per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic eyes, 121.48<br>± 4.90 μm and non amblyopic eyes was 112.92 ± 4.72 μm with statistical significance (p<0.001). The mean change in central macular thickness (CMT) in amblyopic eyes was 198.50 ± 5.30 μm and non amblyopic eyes was 206.80 ± 3.11 μm with statistical significance (p<0.001). There was significant increase in per-papillary retinal nerve fibre layer (pRNFL) thickness and significant decrease in central macular thickness (CMT) on comparing the amblyopic and the fellow eyes of the same patients.</p> <p><strong>Conclusion:</strong> Central macular thickness (CMT) decreased.........................</p>}, number={1}, journal={Pakistan Armed Forces Medical Journal}, author={Ahmed, Tanveer and Niazi, Khizar and Shah, Sobia Usman and Khan, Junaid Afsar and Bukhsh, Husnain Muhammad and Ashraf, Muhammad Arslan}, year={2021}, month={Feb.}, pages={162–66} }