@article{Mehmood_Alam_Yazdani_Rathore_2019, title={FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN}, volume={69}, url={https://pafmj.org/PAFMJ/article/view/3398}, abstractNote={<p><strong>Objective:</strong> To determine the frequency of Kell blood group antigens (K and k) in blood donors from northernPakistan.</p> <p><strong>Study Design:</strong> Cross sectional study.</p> <p><strong>Place and Duration of Study:</strong> The study was carried out at immunohaematology department of Armed Forces Institute of Transfusion (AFIT) Rawalpindi, Pakistan, from 1st Nov 2017 to 31st Dec 2017.</p> <p><strong>Methodology:</strong> After approval of Ethical Committee of Armed Forces Institute of Transfusion (AFIT) Rawalpindi, the blood samples of 2000 blood donors were collected. Samples were selected by non-probability consecutive sampling technique. After preliminary blood grouping for ABO and Rh D, these samples were phenotyped for K (kelleher) and k (celleno) antigens. Typing was performed on Biorad® automated blood grouping system by column agglutination technique (CAT), strictly following manufacturer’s instructions.</p> <p><strong>Results:</strong> Out of 2000 blood donors, typed for K and k antigens, 1966 were males (98.30%) and 34 were females (1.70%). The frequency of K was 4.05% (81/2000) and that of k was 98.90% (1978/2000). The phenotype K-k+ (95.15%) was most prevalent followed by K+k+ (3.75%), K-k- (0.80%) and K+,k- (0.30%).</p> <p><strong>Conclusion:</strong> K antigen frequency is lower than as reported in Caucasions and Saudi Arabia but higher than Indian and African blood donors. This study confirmed that the k (celleno) blood group antigen was highly prevalent antigen in Pakistani population while the K (kelleher) antigen was present in a relatively lower frequency.</p>}, number={5}, journal={Pakistan Armed Forces Medical Journal}, author={Mehmood, Asad and Alam, Maqbool and Yazdani, Muhammad Sajid and Rathore, Muhammad Ali}, year={2019}, month={Oct.}, pages={977–80} }