@article{Zafar_Virk_Sultan_Rehman_Naz_2019, title={STUDY OF EPIDEMIOLOGICAL AND CLINICAL PROFILE OF CHILDHOOD GUILLAIN-BARRE SYNDROME AT THE CHILDREN’S HOSPITAL, LAHORE}, volume={69}, url={https://pafmj.org/PAFMJ/article/view/3040}, abstractNote={<p><strong>Objective:</strong> To ascertain the demographic profile, diversity of clinical aspects of Guillain-Barre Syndrome (GBS) along with its prognosis.</p> <p><strong>Study Design:</strong> Cross sectional study.</p> <p><strong>Place and Duration of Study:</strong> Department of Pediatric Neurology, The Children’s Hospital Lahore, from Jul 2015 to Dec 2016.</p> <p><strong>Material and Methods:</strong> One hundred and twenty five patients of both genders from the age of 1 to 15 years, fulfilling the inclusion criteria were included in the study. The clinical data were entered into proforma.</p> <p><strong>Results:</strong> Out of the total, 77 (61.6%) were males and 48 (38.4%) were females. History of preceding illness was recorded in 57.6% of the patients and Upper Respiratory Tract Infection (URTI) 31.2% was the most common. 54.4% of the patients had cranial nerve paralysis. Upon electro diagnostic studies including electromyography (EMG) and nerve conduction studies (NCS) and clinical examination, there were 49 patients with acute<br>inflammatory demyelinating polyradiculoneuropathy variant (AIDP), 67 had acute motor axonal neuropathy variant (AMAN), 6 patients having mixed and 3 patients with Miller Fischer syndrome (MFS). Treatment with intravenous immunoglobulins (IVIG) was given keeping in mind the indication. At 6 months follow up visit 89.6% of the patients had good outcome while 10.4% patients had poor outcome.</p> <p><strong>Conclusion:</strong> The results of our study show that GBS is a disease with diverse clinical presentation. With the help of diagnostic facilities like EMG/NCS, well-equipped treatment and IVIG clinical outcome is good.</p>}, number={3}, journal={Pakistan Armed Forces Medical Journal}, author={Zafar, Faisal and Virk, Ahmad Omair and Sultan, Tipu and Rehman, Zia Ur and Naz, Aadarsh}, year={2019}, month={Jun.}, pages={611–16} }