@article{Khan_Asghar_Siyar_Saleem_Safdar_2019, title={ROLE OF PER-OPERATIVE WOUND IRRIGATION IN PROPHYLAXIS OF SURGICAL SITE INFECTION IN CLEAN CONTAMINATED WOUNDS}, volume={69}, url={https://pafmj.org/PAFMJ/article/view/2497}, abstractNote={<p><strong>Objective:</strong></p> <p>To compare per-operative normal saline wound irrigation prior to closure with conventional simple wound closure without irrigation in terms of development of surgical site infection (SSI) in clean contaminated wounds.</p> <p><strong> Study Design:</strong> Randomized controlled trial.</p> <p><strong>Place and Duration of Study:</strong> Department of Surgery, Combined Military Hospital Dera Nawab Sahib, from Nov 2014 to Nov 2016.</p> <p><strong>Material and Methods:</strong></p> <p>Group A and group B had 355 patients each. Group A was subjected to per-operative surgical wound irrigation with 300 ml of normal saline prior to skin closure while group B was subjected to conventional simple closure of surgical wound without any kind of wound irrigation. Development of postoperative SSI was checked till 30th post-operative day (POD). A p-value ≤0.05 was considered statistically significant.</p> <p><strong>Results:</strong></p> <p>Postoperative SSI was comparatively less in group A (4.5%) as compared to group B (10.2%) which was statistically significant (p 0.004).</p> <p><strong>Conclusion:</strong></p> <p>Per-operative surgical wound irrigation was found superior to conventional simple wound closure in terms of development of SSI in clean contaminated cases.</p>}, number={1}, journal={Pakistan Armed Forces Medical Journal}, author={Khan, Raheel and Asghar, Muhammad Usman and Siyar, Falak and Saleem, Muhammad Mudassir and Safdar, Muhammad Hanif Khan}, year={2019}, month={Feb.}, pages={60–64} }