Geriatrics Breast Cancer: Stage at Presentation and Relationship of Various Factors with Advanced Stage

Abstract

Objective: To determine the frequency of various stages of breast cancer at presentation and the relationship of various factors with advanced stage in geriatric patients in Pakistan.

Study Design: Prospective longitudinal study.

Place and Duration of Study: Department of Oncology, Hameed Latif Hospital, Lahore Pakistan, from Feb to Jul 2018.

Methodology: A total of 130 geriatric breast cancer patients between the ages of 60-80 years were included. A biopsy report was noted, which was done in the surgical ward and histopathology was done in the institutional pathology department. The researchers evaluated all the reports. In addition, the stage of the breast cancer documented (stage documented by CT scan chest abdomen and pelvis and bone scan. Chest X-ray and ultrasound abdomen and pelvis report were reviewed in case of CT scan report not available) as per American joint committee on Cancer (AJCC) TNM staging system for breast cancer 8th edition.

Results: Mean age was 69.10 ± 5.89 years. 106 (81.54%) patients were between 60 to 70 years of age. The mean duration of disease was 7.48 ± 3.87 months. 52 (40.0%) geriatrics patients presented in stage IV followed by stage III, II, I as 48 (37.00%), 30 (23.0%) and 00(0.0%) respectively. The long duration of illness has a significant relationship with advanced disease (pvalue<0.05).

Conclusion: Stage IV is the most common stage of breast cancer at presentation in geriatric patients, followed by stages III, II and I, respectively and the long duration of illness has a significant relationship with advanced disease.