PREDICTORS OF MORTALITY WITHIN 8 WEEKS AFTER ENDOSCOPIC TREATMENT OF GASTRIC VARICEAL BLEED WITH N-BUTYL 2-CYANOACRYLATE IN CIRRHOTIC PATIENTS

  • Mahmood Ahmad Services Institute of Medical Sciences, Lahore Pakistan
  • Yasir Mahmud Services Institute of Medical Sciences, Lahore Pakistan
  • Sidra Rasheed Services Institute of Medical Sciences, Lahore Pakistan
  • Muhammad Muaaz Services Institute of Medical Sciences, Lahore Pakistan
  • Muhammad Naeem Afzal Services Institute of Medical Sciences, Lahore Pakistan
  • Muhammad Arif Nadeem Services Institute of Medical Sciences, Lahore Pakistan
Keywords: Cirrhosis, N-butyl 2-Cyanoacrylate, Gastric Varices, Predictors, Mortality, Outcome

Abstract

Objective: To assess the predictors associated with mortality within 8 weeks in patients undergoing endoscopic N-butyl-2- cyanoacrylate treatment.

Study Design: Prospective comparative study.

Place and Duration of Study: Department of Gastroenterology, Services Institute of Medical Sciences, Lahore Pakistan, from Mar 2018 to Mar 2019.

Methodology: A total of 106 patients of gastric variceal bleed were enrolled in the study. Tissue glue was injected into the varix endoscopically and mortality within 8 weeks after endoscopic intervention was noted.

Results: Among the enrolled patients, 65 (61.3%) were male and 41(38.7%) were female. Mortality was noted in 19 (17.9%) patients within 8 weeks after endoscopic therapy. Chi-square analysis showed creatinine >1.5, Child Pugh score >9, MELD score >18, re-bleeding within 7 days, low blood pressure <90/60 at presentation and hepatic encephalopathy as significant predictors of mortality (p<0.005).

Conclusion: Cirrhotic patients undergoing endoscopic injection of gastric varix with N-butyl 2-cyanoacrylate after gastric variceal bleed have high risk of death within 8 weeks.

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Published
2021-08-26
How to Cite
Ahmad, M., Mahmud, Y., Rasheed, S., Muaaz, M., Afzal, M., & Nadeem, M. (2021). PREDICTORS OF MORTALITY WITHIN 8 WEEKS AFTER ENDOSCOPIC TREATMENT OF GASTRIC VARICEAL BLEED WITH N-BUTYL 2-CYANOACRYLATE IN CIRRHOTIC PATIENTS. PAFMJ, 71(4), 1314-17. https://doi.org/10.51253/pafmj.v71i4.3281
Section
Original Articles