CORRELATION OF ANTERIOR CHAMBER DEPTH WITH PERIPAPILLARY NERVE FIBER LAYER THICKNESS

Anterior Chamber Depth With Peripapillary Nerve Fiber Layer Thickness

Abstract

Objective: To determine correlation of anterior chamber depth with peripapillary nerve fiber layer thickness.
Study Design: Descriptive cross sectional study.
Place and Duration of study: Armed Forces Institute of Ophthalmology Rawalpindi, from Apr 2016 to Oct 2016.
Patients and Methods: Anterior chamber depth and peripapillary nerve fiber layer thickness was measured in 200 eyes of 110 patients, between 10-40 years of age. Anterior chamber depth was measured in mm, by taking average of 3 readings, measured by optical biometry (IOL Master, Carl Zeiss Meditec, Dublin whereas average peripapillary retinal nerve fibre layer pRNFL thickness was obtained by taking average of 12 segments RNFL thickness measurement, calculated by Spectral domain optical coherence tomography (SD OCT) (3D OCT-1000 Markll, Topcon Co, Tokyo, Japan) after dilating pupils with one drop of 1% Tropicamide, instilled three times, 10 minutes apart. Three readings were taken for each eye. The mean of the three readings was used for the analysis.Pearson correlation (+1/-1) was calculated between anterior chamber depth, peripapillary nerve fiber layer thickness and age.
Results: Two hundred eyes of 110 patients were included in the study. Both eyes were considered in 90% of the patient, however only Right eye was considered in 6.3% of the patients while left eye in 3.7% of the patients.Mean age of the patients was 26.58 ± 8.88 years. Mean visual acuity of patients measured by log MAR was 0.52 ±0.12. Mean Anterior chamber depth (ACD) of patients was 3.41 ± 0.35 while mean RNFL appeared to be 103.26 ±8.89 um.
Conclusion: It was concluded that anterior chamber depth was neither related significantly with peripapillary
nerve fiber layer nor with age.