ISOLATED FAMILIAL MEDULLARY THYROID CARCINOMA AS PART OF MULTIPLE ENDOCRINE NEOPLASM (MEN-2A
Familial Medullary Thyroid Carcinoma and Men-2a
Abstract
Medullary carcinoma of the thyroid (MTC) is a distinct thyroid carcinoma that originates from the parafollicular C cells of the thyroid gland which produce calcitonin. MTC has a genetic association with multiple endocrine neoplasia (MEN) type 2A and 2B syndromes. Sporadic, or isolated, MTC occurs in 75% of patients1.