Primary neuroendocrine tumors of the liver are seldom seen. This is the case report of 45 years old woman who presented with right upper quadrant vague abdominal pain and low grade fever. On examination a firm mass about 6 × 4 cm was palpable in left hypochondrium and epigastrium. Ultrasound and CT-scan showed mass of left lobe (segment II and III) of liver. There was no evidence of cirrhosis and hepatitis B and C status was negative. The tumor markers were also within normal values. Core biopsy confirmed a tumor of neuroendocrine origin. Octreotide scan was done which confirmed that liver was the primary site of neuroendocrine tumor. Left lobectomy (Segment II & III) was done. The diagnosis was confirmed on histopathology and immune histochemistry of specimen.
Keywords : Immunohistochemistry, Neuroendocrine carcinomas, Octreotide.