Aspergillosis is one of the important causes of life threatening fungal infections in immunocompromised patients.We report the case of a 47 year old asthmatic female patient taking steroid inhalers who presented with headache and change in personality. Her computerized tomographic (CT) scan of brain revealed a space occupying lesion (SOL) in frontal lobes. Excisional biopsy of the lesion revealed aspergillosis. She was treated with voriconazole to which she responded well.
Keywords : Aspergillosis, Space occupying lesion, Voriconazole.