PAKISTAN ARMED FORCES
MEDICAL JOURNAL (Category Y)

A Journal of Army Medical & Dental Corps

Being published since 1956

ISSN (online) 2411-8842
ISSN (print) 0030-9648

VOL 68, No. 3, JUNE 2018

COMPARISON OF EFFICACY OF TELMISARTAN AND ATENOLOL IN MANAGEMENT OF ESSENTIAL HYPERTENSION

Rana Shahid Hafeez, Fawad Ahmad*, Malik Nadeem Azam Khan**

Abstract

Objective: To compare the efficacy of telmisartan and atenolol in management of patients with essential hypertension.
Study Design: Randomized comparative trial.
Place and Duration of Study: Department of Medicine Combined Military Hospital Peshawar, from Feb 2010 to Aug 2010.
Material and Methods: One hundred & eighty patients diagnosed with essential hypertension fulfilling the inclusion criteria were included in study using consecutive non-probability sampling after taking informed consent. Patients were allocated to either telmisartan or atenolol group by using a table of random numbers. Follow up of patients was carried out in 4 visits with recording of sitting systolic and diastolic blood pressures.
Results: Among total of 180 patients, 60% were females and 40% were males. Majority were between age group 56-75 years. Reduction of both systolic and diastolic blood pressures at the end of eight weeks was significantly greater with telmisartan as compared to atenolol (p-value=0.000 and 0.016 respectively).
Conclusion: At the end of eight weeks of treatment, telmisartan was more effective than atenolol in lowering systolic and diastolic blood pressure.

Keywords : Atenolol, Diastolic blood pressure (DBP), Essential hypertension, Systolic blood pressure (SBP), Telmisartan.



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