Objective: To study the pattern of cognitive impairment after giving total intravenous anesthesia Vs general
anesthesia for ECT for patients of Depressive Episode Severe.
Study Design: Randomized controlled trial.
Place and Duration of Study: Combined Military Hospital Skardu, from 15 Jul 2015 till 15 Jan 2016.
Material and Methods: Hundred patients fulfilling the inclusion criteria were included by consecutive sampling technique for this study and divided in to two groups of 50 each. Patients of group A were given TIVA (propofol + succinylcholine). Patients in group B received GA (propofol + succinylcholine + isoflurane). Cognitive functions of patient were assessed by psychiatrist via mini mental state examination (MMSE) test before ECT and two weeks after ECT respectively.
Results: Both the groups were assessed for cognitive impairment after TIVA Vs GA. In group A the MMSE
showed less cognitive impairment as compared to group B (p<0.05).
Conclusion: Cognitive impairment is less in total intravenous anesthesia as compared to general anesthesia for ECT in patients of depressive episode severe.
Keywords : Anesthesia general, Anesthesia intravenous, Depressive disorder, Electroconvulsive therapy, Neuropsychological test.