PAKISTAN ARMED FORCES
MEDICAL JOURNAL (Category Y)

A Journal of Army Medical & Dental Corps

Being published since 1956

ISSN (online) 2411-8842
ISSN (print) 0030-9648

VOL 67, No. 5, OCTOBER 2017

PATTERN OF COGNITIVE IMPAIRMENT AFTER GIVING TOTAL INTRAVENOUS ANAESTHESIA VS GENERAL ANAESTHESIA FOR ELECTROCONVULSIVE THERAPY IN PATIENTS WITH DEPRESSIVE EPISODE SEVERE

Usman Eijaz Malik, Nadeem Ahmed, Raza Rahim Hyder

Abstract

Objective: To study the pattern of cognitive impairment after giving total intravenous anesthesia Vs general
anesthesia for ECT for patients of Depressive Episode Severe.
Study Design: Randomized controlled trial.
Place and Duration of Study: Combined Military Hospital Skardu, from 15 Jul 2015 till 15 Jan 2016.
Material and Methods: Hundred patients fulfilling the inclusion criteria were included by consecutive sampling technique for this study and divided in to two groups of 50 each. Patients of group A were given TIVA (propofol + succinylcholine). Patients in group B received GA (propofol + succinylcholine + isoflurane). Cognitive functions of patient were assessed by psychiatrist via mini mental state examination (MMSE) test before ECT and two weeks after ECT respectively.
Results: Both the groups were assessed for cognitive impairment after TIVA Vs GA. In group A the MMSE
showed less cognitive impairment as compared to group B (p<0.05).
Conclusion: Cognitive impairment is less in total intravenous anesthesia as compared to general anesthesia for ECT in patients of depressive episode severe.

Keywords : Anesthesia general, Anesthesia intravenous, Depressive disorder, Electroconvulsive therapy, Neuropsychological test.



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